🐾Canine nutrition begins with the microbiome.

SCIENCE-DRIVEN CANINE NUTRITION

Healthy gut.
Happier days.

Daily digestive support built on modern microbiome science.
Formulated by Ph.D. scientists in animal nutrition and food microbiology.

  • 5 Billion CFU

    5 Probiotic strains
    + Prebiotics + Postbiotics

  • Ph.D. Scientists

    Animal Nutrition + Food Microbiology

  • 60 Servings

    Convenient daily powder

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Daily support, designed around the gut.

  • One thoughtfully formulated product.
  • Every ingredient has a purpose.
  • Every scoop supports a healthier gut microbiome.

DAILY ESSENTIAL

Gut Balance

$34.95

Science-driven microbiome support for digestive health and a balanced gut ecosystem.

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Developed & Made in the USA

Feeding Directions

Daily Suggested Amount
1 scoop (2g)

WeightDaily Amount
2–24 lbs½ scoop
25–49 lbs1 scoop
50–74 lbs1 ½ scoops
75+ lbs2 scoops

Mix with food or sprinkle over food once daily.

The daily amount can be divided between AM and PM.

1 scoop (2 g) is approximately ½ teaspoon.

Ingredients

Active Ingredients Per Serving (2 g)

Gut Balance Blend260 mg
  • Fructooligosaccharides (FOS)
  • Beta Glucan 1,3/1,6
    (from Saccharomyces cerevisiae)
  • Tributyrin
Probiotic Blend
5 Billion CFU*
42.5 mg
  • Bacillus subtilis
  • Lactobacillus plantarum
  • Enterococcus faecium
  • Lactobacillus acidophilus
  • Bifidobacterium animalis subsp. lactis BLa80

*5 Billion CFU at the time of manufacture

THE PROMISE

Support where wellbeing begins.

Built around the gut –
a dynamic ecosystem at the center of digestive health

Person walking a dog through a calm natural landscape

01

Helps maintain a balanced gut microbiome

02

Helps nourish beneficial gut bacteria

03

Supports a healthy intestinal environment

04

Supports healthy digestion and nutrient utilization

EXPLORE MORE

A closer look at what makes the difference.

Four perspectives. One purpose.

Discover the story, science, formulation, and care behind CanineBiome.

OUR STORY

A healthier future
for the dogs we love.

Rooted in care. Guided by science.

Explore our story →
Gut–brain axis, Gut–liver axis, Gut–skin axis ONE CENTRALECOSYSTEMGut–liver axisGut–skin axisGut–brain axis

THE SCIENCE

More than digestion.
A connected system.

Explore how the gut microbiome interacts with systems throughout the body

Explore the science →

THE FORMULA

Carefully selected.
Purposefully combined.

Probiotics, prebiotics, and postbiotics brought together in a thoughtful, microbiome-focused formula

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QUALITY & SAFETY

Care is a standard,
not a claim.

From ingredient selection to finished product, quality guides every step

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Happy Tails, Everyday Stories

JOURNAL

Latest from the Blog

Article

The Gut-Brain Axis in Dogs

For many years, the brain was considered the sole control center of the body. The gut was viewed primarily as a digestive organ, responsible for processing food and absorbing nutrients. Modern research suggests a more interconnected picture. The gut and the brain communicate continuously through a bidirectional network known as the gut-brain axis. What is the Gut-Brain Axis? The gut-brain axis refers to the communication pathways that link the gastrointestinal tract and the central nervous system. These connections occur through: -      The vague nerve -      Immune signaling molecules -      Hormonal pathways -      Microbial metabolites The gut is not simply receiving instructions from the brain. It is actively sending information back. The Role of the Microbiome The microbiome plays a central role in this communication. Certain gut bacteria produce metabolites such as short-chain fatty acids, including butyrate. These compounds can influence: -      Intestinal barrier integrity -      Local immune responses -      Signaling pathways that interact with the nervous system While research in dogs is still evolving, animal models consistently demonstrate microbiome involvement in gut-brain communication. Stress and Digestion Many dog parents have observed that stress can influence digestion. Travel, environmental changes, or routine disruptions may lead to temporary digestive changes. This is an example of the gut-brain axis in action. The brain influences gut mobility and secretion. The gut, in turn, sends signals back that can influence behavior and mood. Why This Matters The gut-brain axis does not suggest that digestion controls behavior. Rather, it highlights that multiple systems interact in dynamic ways. Supporting a stable gut environment may help maintain balanced communication between the digestive system and the nervous system.   Simple Diagram Supporting the Microbiome is One Foundational Way to Promote Digestive Balance and Healthy System-Wide Communication in Dogs  

Introduction

The Gut is the Commander Center

The digestive tract is more than a place where food is broken down. It is a dynamic ecosystem that communicates with the immune system, the skin, metabolism, and even behavior. At CanineBiome, we explore how the gut microbiome functions as a biological command center and how thoughtful synbiotic design can support whole-body balance in dogs. Our articles are written in a calm, educational tone to help dog parents understand the science behind probiotics, prebiotics, and postbiotics – without exaggeration, trends, or marketing noise. 

Article

The Gut is the Command Center of Dog’s Health

Most dog parents think of the gut as a digestive tube – a place where food is broken down and nutrients are absorbed. But modern science shows something much more powerful. The gut is not just a digestive organ. It is a communication hub that interacts with the immune system, the brain, metabolism, and even skin.   The Microbiome: A living Ecosystem Inside the intestines lives a vast ecosystem of bacteria known as the microbiome. These microbes are not passive passengers. They actively interact with intestinal cells and send signals throughout the body. When balanced, this ecosystem helps maintain: -      Normal digestion -      Healthy immune responses -      A strong intestinal lining When disrupted, communication becomes less stable. The Intestinal Barrier The gut lining is only one cell thick. It acts as a selective barrier, allowing nutrients to pass while keeping unwanted substances out. Microbial metabolites such as short-chain fatty acids – including butyrate – help nourish these cells. This is one reason microbiome balance matters beyond digestion. Why This Matters Supporting the gut is not just about stool quality. It is about maintaining the foundation of multiple physiological systems. The Gut Works Quietly – But It Influences Much More Than We Once Thought.

Thoughtful science.Made practical for every day.

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